Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Equus Caballus (horse)
TISSUE(S): Adipose-derived Stem Cell, Mesenchymal Cell, Bone Marrow Stem Cell
SUBMITTER: Philip Brownridge
LAB HEAD: Agnieszka Turlo
PROVIDER: PXD039652 | Pride | 2024-01-26
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
KA_210322_A10_neat_2hr.mgf | Mgf | |||
KA_210322_A10_neat_2hr.mzid.gz | Mzid | |||
KA_210322_A10_neat_2hr.raw | Raw | |||
KA_210322_A11_neat_2hr.mgf | Mgf | |||
KA_210322_A11_neat_2hr.mzid.gz | Mzid |
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Turlo Agnieszka J AJ Hammond Dean E DE Ramsbottom Kerry A KA Soul Jamie J Gillen Alexandra A McDonald Kieran K Peffers Mandy J MJ
Stem cells (Dayton, Ohio) 20231101 11
Variation in mesenchymal stromal cell (MSC) function depending on their origin is problematic, as it may confound clinical outcomes of MSC therapy. Current evidence suggests that the therapeutic benefits of MSCs are attributed to secretion of biologically active factors (secretome). However, the effect of donor characteristics on the MSC secretome remains largely unknown. Here, we examined the influence of donor age, sex, and tissue source, on the protein profile of the equine MSC secretome. We ...[more]