Dataset Information

Quantitative proteomics reveals significant variation in host responses of cattle with differing buffalo fly susceptibility

ABSTRACT: This project aimed to characterise the immune response of cattle to buffalo fly infestation using cattle serum samples. The cattle were phenotyped into two groups, high buffalo fly burden and low buffalo fly burden cattle, following exposure to buffalo flies. The SWATH analysis was sued to measure the relative abundance of proteins in serum samples of the two groups at different time points.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Bos Taurus (bovine)

TISSUE(S): Blood Serum

SUBMITTER: Ali Raza

LAB HEAD: Dr Peter

PROVIDER: PXD039655 | Pride | 2024-08-08

REPOSITORIES: Pride

ACCESS DATA

Dataset's files

Source:

			Action	DRS
	20220309_QAFFI_Kamran_DDA_X-F1.group	Other
	20220309_QAFFI_Kamran_DDA_X-F1.swath	Other
	20220309_QAFFI_Kamran_SWATH_H0-01.wiff	Wiff
	20220309_QAFFI_Kamran_SWATH_H0-01.wiff.scan	Wiff
	20220309_QAFFI_Kamran_SWATH_H0-02.wiff	Wiff

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Publications

Quantitative proteomics reveals significant variation in host responses of cattle with differing buffalo fly susceptibility.

Kamran Muhammad M Raza Ali A Naseem Muhammad N MN Turni Conny C Tabor Ala E AE James Peter P

Frontiers in immunology 20240716

<h4>Background</h4>Control of buffalo flies (<i>Haematobia irritans exigua</i>, BFs) relies mainly on chemical methods; however, resistance to insecticides is widespread in BF populations. Breeding for resistance to BFs represents a possible alternative, but direct phenotyping of animals is laborious and often inaccurate. The availability of reliable diagnostic biomarker(s) to identify low BF carrier cattle would facilitate rapid and accurate selection for genetic improvement. However, limited i ...[more]

PMID: 39086482

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