Proteomics

Dataset Information

0

Quantitative proteomics reveals significant variation in host responses of cattle with differing buffalo fly susceptibility


ABSTRACT: This project aimed to characterise the immune response of cattle to buffalo fly infestation using cattle serum samples. The cattle were phenotyped into two groups, high buffalo fly burden and low buffalo fly burden cattle, following exposure to buffalo flies. The SWATH analysis was sued to measure the relative abundance of proteins in serum samples of the two groups at different time points.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Bos Taurus (bovine)

TISSUE(S): Blood Serum

SUBMITTER: Ali Raza  

LAB HEAD: Dr Peter

PROVIDER: PXD039655 | Pride | 2024-08-08

REPOSITORIES: Pride

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Publications

Phased ERK-responsiveness and developmental robustness regulate teleost skin morphogenesis

Ramkumar Nitya N   Richardson Christian C   O’Brien Makinnon M   Butt Faraz Ahmed FA   Park Jieun J   Chao Anna AT   Bagnat Michel M   Poss Kenneth K   Di Talia Stefano S  

20240514


Elongation of the vertebrate embryonic axis necessitates rapid expansion of the epidermis to accommodate the growth of underlying tissues. Here, we generated a toolkit to visualize and quantify signaling in entire cell populations of periderm, the outermost layer of the epidermis, in live developing zebrafish. We find that oriented cell divisions facilitate growth of the early periderm during axial elongation rather than cell addition from the basal layer. Activity levels of ERK, a downstream ef  ...[more]