Proteomics

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Serum proteome profiles in patients treated with targeted temperature management after out-of-hospital cardiac arrest

ABSTRACT: This pilot study aimed to investigate serum proteome profiles from unconscious patients admitted to hospital after out-of-hospital cardiac arrest according to temperature treatment and neurological outcome.

INSTRUMENT(S): Q Exactive HF-X

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Serum

DISEASE(S): Cardiac Arrest

SUBMITTER: Anahita Bakochi  

LAB HEAD: Sven Kjellström

PROVIDER: PXD040592 | Pride | 2023-10-24

REPOSITORIES: Pride

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Serum proteome profiles in patients treated with targeted temperature management after out-of-hospital cardiac arrest.

Lileikyte Gabriele G   Bakochi Anahita A   Ali Ashfaq A   Moseby-Knappe Marion M   Cronberg Tobias T   Friberg Hans H   Lilja Gisela G   Levin Helena H   Årman Filip F   Kjellström Sven S   Dankiewicz Josef J   Hassager Christian C   Malmström Johan J   Nielsen Niklas N  

Intensive care medicine experimental 20230717 1

<h4>Background</h4>Definition of temporal serum proteome profiles after out-of-hospital cardiac arrest may identify biological processes associated with severe hypoxia-ischaemia and reperfusion. It may further explore intervention effects for new mechanistic insights, identify candidate prognostic protein biomarkers and potential therapeutic targets. This pilot study aimed to investigate serum proteome profiles from unconscious patients admitted to hospital after out-of-hospital cardiac arrest a  ...[more]

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