Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Heart, Fibroblast
DISEASE(S): Myocardial Ischemia
SUBMITTER: Andrew Keller
LAB HEAD: Dr James Edward Bruce
PROVIDER: PXD040864 | Pride | 2024-10-17
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 33 |
Keller Andrew A Tang Xiaoting X Bruce James E JE
Journal of proteome research 20230808 9
Chemical cross-linking with mass spectrometry provides low-resolution structural information on proteins in cells and tissues. Combined with quantitation, it can identify changes in the interactome between samples, for example, control and drug-treated cells or young and old mice. A difference can originate from protein conformational changes that alter the solvent-accessible distance separating the cross-linked residues. Alternatively, a difference can result from conformational changes localiz ...[more]