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Semen proteome analysis comparing the persistent effects of different SARS-COV-2 variants on male reproductive system in recovered men

ABSTRACT: After the initial COVID-19 wave, India experienced a second COVID-19 wave in March 2021, which was driven by the delta variant. By January 2021, India has also begun its vaccine campaign. Therefore, semen samples from recovered patients who were infected during the two waves of COVID-19 in India were obtained to study the impact of variants on the male reproductive system. We compared samples from the second wave with those of first wave in India. We also included control samples to the comparison.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Semen

SUBMITTER: Avinash singh

LAB HEAD: sanjeeva srivastava

PROVIDER: PXD041904 | Pride | 2024-01-26

REPOSITORIES: Pride

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	21122021_Fusion_COVID_SEMEN_SCT49.raw	Raw
	21122021_Fusion_COVID_SEMEN_SCT50.raw	Raw
	21122021_Fusion_COVID_SEMEN_SCT51.raw	Raw
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Publications

Semen proteomics reveals alterations in fertility-related proteins post-recovery from COVID-19.

Dash Ankita A Salkar Akanksha A Nissa Mehar Un MU Makwana Prashant P Athalye Arundhati A Parikh Swapneil S Srivastava Sanjeeva S Parikh Firuza F

Frontiers in physiology 20231109

<b>Introduction:</b> Changes to sperm quality and decline in reproductive function have been reported in COVID-19-recovered males. Further, the emergence of SARS-CoV-2 variants has caused the resurgences of COVID-19 cases globally during the last 2 years. These variants show increased infectivity and transmission along with immune escape mechanisms, which threaten the already burdened healthcare system. However, whether COVID-19 variants induce an effect on the male reproductive system even afte ...[more]

PMID: 38028760

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