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Involvement of the microenvironment in the VC-Resist glioblastoma cells

ABSTRACT: In order to understand which molecular mechanisms are involved in radiation resistance and tumor propagation of glioblastoma, our laboratory has developed in-vitro models capable of mimicking the perivascular niche. Indeed, our laboratory hypothesizes that this niche is essential for glioblastoma cells to acquire a radioresistant character. That is why we are considering culturing our glioblastoma cells (GL261 cells) with the factors secreted by the perivascular niche (conditioned medium of mouse brain blood vessels) in order to study which phosphoproteins are activated in the presence of these factors. In parallel, a RNA sequencing analysis was carried out

INSTRUMENT(S): Orbitrap Eclipse, Orbitrap Exploris 480

ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse)

TISSUE(S): Brain, Glioblastoma Cell Line

SUBMITTER: Vanessa Masson

LAB HEAD: Damarys Loew

PROVIDER: PXD042606 | Pride | 2024-01-23

REPOSITORIES: Pride

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			Action	DRS
	Design_PRIDE.xlsx	Xlsx
	E1331FD.msf	Msf
	E1331FD.raw	Raw
	E1332FD.msf	Msf
	E1332FD.raw	Raw

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