Proteomics

Dataset Information

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A proteomic classifier panel for early screening of colorectal cancer


ABSTRACT: Colorectal cancer (CRC) is a leading cause of cancer-related death. Diagnosis at an early stage can greatly improve the patient outcome. Therefore, developing sensitive and specific non-invasive screening and diagnostic methods has a tremendous potential to combat the disease.

INSTRUMENT(S): Orbitrap Exploris 240

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Plasma

DISEASE(S): Colon Cancer

SUBMITTER: Tingting Wang  

LAB HEAD: Lujian Liao

PROVIDER: PXD042639 | Pride | 2024-05-24

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
202102_CRC_dia_01.raw Raw
202102_CRC_dia_02.raw Raw
202102_CRC_dia_03.raw Raw
202102_CRC_dia_04.raw Raw
202102_CRC_dia_05.raw Raw
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Publications

A proteomic classifier panel for early screening of colorectal cancer: a case control study.

Hua Hanju H   Wang Tingting T   Pan Liangxuan L   Du Xiaoyao X   Xia Tianxue T   Fa Zhenzhong Z   Gu Lei L   Gao Fei F   Yu Chaohui C   Gao Feng F   Liao Lujian L   Shen Zhe Z  

Journal of translational medicine 20240221 1


<h4>Background</h4>Diagnosis of colorectal cancer (CRC) during early stages can greatly improve patient outcome. Although technical advances in the field of genomics and proteomics have identified a number of candidate biomarkers for non-invasive screening and diagnosis, developing more sensitive and specific methods with improved cost-effectiveness and patient compliance has tremendous potential to help combat the disease.<h4>Methods</h4>We enrolled three cohorts of 479 subjects, including 226  ...[more]

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