Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Saliva
SUBMITTER: Zhuo Chen
LAB HEAD: Zheng Li
PROVIDER: PXD043185 | Pride | 2023-10-24
REPOSITORIES: Pride
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CZ_2_global_20210917_1.raw | Raw |
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Chen Zhuo Z Chen Xiangqin X Zhu Bojing B Yu Hanjie H Bao Xiaojuan X Hou Yao Y Song Wanghua W Sun Shisheng S Li Zheng Z
Journal of proteome research 20230807 9
Aging-related salivary gland degeneration usually causes poor oral health. Periductal fibrosis frequently occurs in the submandibular gland of the elderly. Transforming growth factor β1 (TGF-β1) is the primary driving factor for fibrosis, which exhibits an increase in the fibrotic submandibular gland tissue. This study aimed to investigate the effects of TGF-β1 on the human submandibular gland (HSG) cell secretory function and its influences on aquaporin 5 (AQP5) expressions and distribution. We ...[more]