Proteomics

Dataset Information

0

Mouse embryonic tail tendon bundle time series


ABSTRACT: Laser capture microdissection mass spectrometry analysis on mouse embryonic tail tendon bundles, E12.5-E14.5 in half day steps.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Tendon

SUBMITTER: Joan Chang  

LAB HEAD: Joan Chang

PROVIDER: PXD043811 | Pride | 2023-07-19

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20220916_6pm_Std_GTU_04-07.pdf Pdf
20220916_6pm_Std_GTU_04.raw Raw
20220916_6pm_Std_GTU_05.raw Raw
20220916_6pm_Std_GTU_06.raw Raw
20220916_6pm_Std_GTU_07.raw Raw
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Publications

Modeling collagen fibril self-assembly from extracellular medium in embryonic tendon.

Revell Christopher K CK   Herrera Jeremy A JA   Lawless Craig C   Lu Yinhui Y   Kadler Karl E KE   Chang Joan J   Jensen Oliver E OE  

Biophysical journal 20230705 16


Collagen is a key structural component of multicellular organisms and is arranged in a highly organized manner. In structural tissues such as tendons, collagen forms bundles of parallel fibers between cells, which appear within a 24-h window between embryonic day 13.5 (E13.5) and E14.5 during mouse embryonic development. Current models assume that the organized structure of collagen requires direct cellular control, whereby cells actively lay down collagen fibrils from cell surfaces. However, su  ...[more]

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