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Role of Rab11 in Enterovirus A71 (EV-A71) infection

ABSTRACT: A siRNA screening using a commercially available membrane trafficking library identified Rab11 as a pro-viral host factor in motor neuron NSC34 cell line infected with EV-A71, a major causative agent of Hand, Foot and Mouth Disease (HFMD). This project aims at deciphering the role of Rab11 during EV-A71 infection by using various molecular virology and cell biology approaches. We also identified Rab11 interacting partners during EV-A71 infection by pulldown and mass spectrometry.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human) Enterovirus A71

SUBMITTER: Qing Yong Ng

LAB HEAD: Sylvie Alonso

PROVIDER: PXD043870 | Pride | 2024-06-28

REPOSITORIES: Pride

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