Proteomics

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Proteomic analysis of breast cancer based on immune subtypes


ABSTRACT: Immunotherapy is applied to breast cancer to resolve the limitations of survival gain in existing treatment modalities. With immunotherapy, a tumor can be classified into immune-inflamed, excluded and desert based on the distribution of immune cells. We assessed the clinicopathological features, each subtype’s prognostic value and differentially expressed proteins between immune subtypes.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

DISEASE(S): Breast Cancer

SUBMITTER: Kyunggon Kim  

LAB HEAD: Kyunggon Kim

PROVIDER: PXD043902 | Pride | 2024-06-16

REPOSITORIES: Pride

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Publications

Proteomic analysis of breast cancer based on immune subtypes.

Jeon Yeonjin Y   Lee GunHee G   Jeong Hwangkyo H   Gong Gyungyub G   Kim JiSun J   Kim Kyunggon K   Jeong Jae Ho JH   Lee Hee Jin HJ  

Clinical proteomics 20240229 1


<h4>Background</h4>Immunotherapy is applied to breast cancer to resolve the limitations of survival gain in existing treatment modalities. With immunotherapy, a tumor can be classified into immune-inflamed, excluded and desert based on the distribution of immune cells. We assessed the clinicopathological features, each subtype's prognostic value and differentially expressed proteins between immune subtypes.<h4>Methods</h4>Immune subtyping and proteomic analysis were performed on 56 breast cancer  ...[more]

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