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Human lung cancer TMT-labeling LC-MS

ABSTRACT: Although the paradigm of cancer treatment has changed with the recent development of drugs targeting immune checkpoints (PD-1, PD-L1, etc.), there is still a need for new targets for anticancer drugs. To discover new potential targets for immunotherapy, we compared membrane protein expression in non-small cell lung cancer cells versus normal lung cancer cells and NSCLC cell lines with low and high PD-L1 expression using mass spectrometry. As a result, it was confirmed that membrane protein, which is one of the most highly expressed proteins in NSCLC cell lines, is highly expressed in normal cells and highly expressed in cells with low PD-L1 expression.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Lung

SUBMITTER: Jae-Sik Shin

LAB HEAD: Jae-Sik Shin

PROVIDER: PXD044086 | Pride | 2024-01-08

REPOSITORIES: Pride

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			Action	DRS
	20221007_NFT.mzML	Mzml
	20221007_NFT.raw	Raw
	DTASelect-filter.mzid	Mzid

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