Proteomics

Dataset Information

0

Targeting IRE1α reprograms the tumor microenvironment and enhances anti-tumor immunity in prostate cancer


ABSTRACT: Unfolded protein response (UPR) is a central stress response pathway in normal cells that is hijacked by tumor cells for their survival. However, how activation of UPR in cancer cells shapes the tumor microenvironment (TME) remain largely unexplored. Here, we investigated the role of IRE1α-XBP1s on modulation of TME dynamics in prostate cancer (PCa).

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Prostate Gland, Prostate Epithelium

DISEASE(S): Prostate Adenocarcinoma

SUBMITTER: Frank Stein  

LAB HEAD: Fahri Saatcioglu

PROVIDER: PXD044287 | Pride | 2024-08-28

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
F117024.dat Other
F117026.dat Other
F117027.dat Other
F117028.dat Other
F117029.dat Other
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