Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behavior

ABSTRACT: Proximity labeling/BioID analysis of LRR7/Densin-180 293T cells were transfected with emty BioID vectors coding for LRR/BioID or full-length Densin-180/BioID fusion proteins. After treatment with Biotin,cells were lysed in RIPA(samples 1-6) or IP(samples 7-9)buffer. Biotinylated proteins were purified using strepavidin beads and processed for mass spectrodcopic analysis

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Bente Siebels  

LAB HEAD: Hans-Jürgen Kreienkamp

PROVIDER: PXD044289 | Pride | 2024-08-15

REPOSITORIES: Pride