Ontology highlight
ABSTRACT:
INSTRUMENT(S): impact II
ORGANISM(S): Rattus Norvegicus (rat)
TISSUE(S): Liver, Bile
SUBMITTER: Simon Moosburner
LAB HEAD: Prof. Dr. Igor M. Sauer
PROVIDER: PXD045394 | Pride | 2024-08-09
REPOSITORIES: Pride
Action | DRS | |||
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Legend.rtf | Other | |||
bile31.d.zip | Other | |||
bile31.mgf | Mgf | |||
bile31.xml | Xml | |||
bile32.d.zip | Other |
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Zimmer Maximilian M Hillebrandt Karl Herbert KH Roschke Nathalie Nora NN Lippert Steffen S Klein Oliver O Nebrich Grit G Gassner Joseph Maria George Vernon JMGV Strobl Felix F Pratschke Johann J Krenzien Felix F Sauer Igor Maximilian IM Raschzok Nathanael N Moosburner Simon S
European journal of medical research 20240711 1
<h4>Background</h4>Liver grafts are frequently declined due to high donor age or age mismatch with the recipient. To improve the outcome of marginal grafts, we aimed to characterize the performance of elderly vs. young liver grafts in a standardized rat model of normothermic ex vivo liver machine perfusion (NMP).<h4>Methods</h4>Livers from Sprague-Dawley rats aged 3 or 12 months were procured and perfused for 6 h using a rat NMP system or collected as a reference group (n = 6/group). Tissue, bil ...[more]