Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Mus Musculus (mouse)
SUBMITTER: Benjamin Van Espen
LAB HEAD: Ze'ev Ronai
PROVIDER: PXD045473 | Pride | 2024-08-09
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
P001768_plko_1.raw | Raw | |||
P001768_plko_2.raw | Raw | |||
P001768_plko_3.raw | Raw | |||
P001768_sh185_1.raw | Raw | |||
P001768_sh185_2.raw | Raw |
Items per page: 1 - 5 of 11 |
Molecular cancer research : MCR 20240101 1
RNF185 is a RING finger domain-containing ubiquitin ligase implicated in ER-associated degradation. Prostate tumor patient data analysis revealed a negative correlation between RNF185 expression and prostate cancer progression and metastasis. Likewise, several prostate cancer cell lines exhibited greater migration and invasion capabilities in culture upon RNF185 depletion. Subcutaneous inoculation of mouse prostate cancer MPC3 cells stably expressing short hairpin RNA against RNF185 into mice re ...[more]