Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos, Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Christina Woo
LAB HEAD: Christina M. Woo
PROVIDER: PXD045676 | Pride | 2024-05-07
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 28 |
Duque Mark Anthony Leon MAL Vallavoju Nandini N Zhang Tiffany T Yvon Robert R Pan Ying-Xian YX Woo Christina M CM
Chembiochem : a European journal of chemical biology 20240219 6
The opioids are powerful analgesics yet possess contingencies that can lead to opioid-use disorder. Chemical probes derived from the opioid alkaloids can provide deeper insight into the molecular interactions in a cellular context. Here, we designed and developed photo-click morphine (PCM-2) as a photo-affinity probe based on morphine and dialkynyl-acetyl morphine (DAAM) as a metabolic acetate reporter based on heroin. Application of these probes to SH-SY5Y, HEK293T, and U2OS cells revealed that ...[more]