Proteomics

Dataset Information

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ARK Study Urinary Proteome Hypertension


ABSTRACT: The study aimed to identify potential proteins and pathways involved in hypertension-associated albuminuria by assessing urinary proteomic profiles in black South African participants with combined hypertension and albuminuria compared to those who have neither condition.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Urine

SUBMITTER: Ireshyn Govender  

LAB HEAD: Previn Naicker

PROVIDER: PXD046441 | Pride | 2024-05-24

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
ARK0001.wiff Wiff
ARK0001.wiff.scan Wiff
ARK0014.wiff Wiff
ARK0014.wiff.scan Wiff
ARK0036.wiff Wiff
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Publications

Proteomic insights into the pathophysiology of hypertension-associated albuminuria: Pilot study in a South African cohort.

Govender Melanie A MA   Stoychev Stoyan H SH   Brandenburg Jean-Tristan JT   Ramsay Michèle M   Fabian June J   Govender Ireshyn S IS  

Clinical proteomics 20240224 1


<h4>Background</h4>Hypertension is an important public health priority with a high prevalence in Africa. It is also an independent risk factor for kidney outcomes. We aimed to identify potential proteins and pathways involved in hypertension-associated albuminuria by assessing urinary proteomic profiles in black South African participants with combined hypertension and albuminuria compared to those who have neither condition.<h4>Methods</h4>The study included 24 South African cases with both hyp  ...[more]

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