Dataset Information

Integrative proteomic and metabonomic profiling elucidate amino acid and lipid metabolism disorder in CA-MRSA infected human breast abscesses

ABSTRACT: The CA-MRSA- or MSSA-infected pus samples of breast abscess were collected for the followed dual-omics studies. For label-free analysis, five CAMRSA and five MSSA samples were used, followed by PRM validation of candidate biomarkers.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Serum, Neutrophil

DISEASE(S): Breast Abscess

SUBMITTER: Xiao Guan

LAB HEAD: Xiao Guan

PROVIDER: PXD046678 | Pride | 2024-01-26

REPOSITORIES: Pride

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			Action	DRS
	P101SC17092255-01.match_result.tar.gz	Other
	P101SC17092255-01.raw_file.tar.gz	Raw
	checksum.txt	Txt

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Integrative proteomic and metabonomic profiling elucidates amino acid and lipid metabolism disorder in CA-MRSA-infected breast abscesses.

Yin Yongshuo Y Cao Lina L Zhang Meng M Li Yingjie Y Sun Chunhua C Ma Qinghua Q Liu Zhaoyun Z Li Chao C Yu Zhiyong Z Guan Xiao X

Frontiers in cellular and infection microbiology 20231113

<h4>Objective</h4>Bacterial culture and drug sensitivity testing have been the gold standard for confirming community-acquired methicillin-resistant <i>Staphylococcus aureus</i> (CA-MRSA) infection in breast abscess with a long history. However, these tests may delay treatment and increase the risk of nosocomial infections. To handle and improve this critical situation, this study aimed to explore biomarkers that could facilitate the rapid diagnosis of CA-MRSA infection.<h4>Methods</h4>This stud ...[more]

PMID: 38029258

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