Proteomics

Dataset Information

0

Proteomic analysis of small extracellular vesicles derived from human iPSC


ABSTRACT: Pluripotent stem cell-derived small extracellular vesicles (PSC-sEVs) have demonstrated great clinical translational potential in multiple aging-related degenerative diseases. Characterizing the PSC-sEVs is crucial for their clinical applications. However, the specific biomarker pattern of PSC-sEVs remains unknown. We displayed proteome analysis and further verification for identification of PSC-sEVs' specific biomarkers. The application of these specific biomarkers for PSC-sEVs identification may advance the clinical translation of PSCs-sEVs.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Embryonic Stem Cell

DISEASE(S): Disease Free

SUBMITTER: Zhengsheng Chen  

LAB HEAD: Yang Wang

PROVIDER: PXD047171 | Pride | 2024-05-23

REPOSITORIES: Pride

altmetric image

Publications

Identification of specific markers for human pluripotent stem cell-derived small extracellular vesicles.

Chen Zhengsheng Z   Luo Lei L   Ye Teng T   Zhou Jiacheng J   Niu Xin X   Yuan Ji J   Yuan Ting T   Fu Dehao D   Li Haiyan H   Li Qing Q   Wang Yang Y  

Journal of extracellular vesicles 20240201 2


Pluripotent stem cell-derived small extracellular vesicles (PSC-sEVs) have demonstrated great clinical translational potential in multiple aging-related degenerative diseases. Characterizing the PSC-sEVs is crucial for their clinical applications. However, the specific marker pattern of PSC-sEVs remains unknown. Here, the sEVs derived from two typical types of PSCs including induced pluripotent stem cells (iPSC-sEVs) and embryonic stem cells (ESC-sEVs) were analysed using proteomic analysis by l  ...[more]

Similar Datasets

2021-08-30 | PXD018655 | Pride
2022-12-08 | PXD037294 | Pride
2021-08-07 | E-MTAB-9462 | biostudies-arrayexpress
2022-05-20 | PXD032674 | Pride
2020-12-02 | PXD013026 | Pride
2024-04-13 | PXD051347 | Pride
2019-04-30 | PXD010762 | Pride
2020-12-15 | PXD022576 | Pride
2023-08-01 | PXD040458 | Pride
2023-07-20 | PXD026197 | Pride