Bioactive decellularized extracellular matrix-based hydrogel supports human adipose tissue-derived stem cell maintenance and fibrocartilage phenotype
Ontology highlight
ABSTRACT: Decellularized extracellular matrix (dECM)-based hydrogels combined with hASCs could serve as an interface for studying behavior and differentiation properties in a cartilage microenvironment. In the present study, we described the behavior of hASCs cultured in a commercial dECM MatriXpec™. The protein composition of MatriXpec™ was accessed by mass spectrometry and is mainly represented by collagen proteins, building an hydrogel fibrous ultrastructure.
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Sus Scrofa Domesticus (domestic Pig)
TISSUE(S): Chondrocyte, Tendon
DISEASE(S): Cartilage Disease
SUBMITTER: Marco Augusto Stimamiglio
LAB HEAD: Marco Augusto Stimamiglio
PROVIDER: PXD047464 | Pride | 2023-12-22
REPOSITORIES: Pride
ACCESS DATA