Proteomics

Dataset Information

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Inhalation of ACE2-expressing lung spheroid cell exosomes provides prophylactic protection against SARS-CoV-2


ABSTRACT: We demonstrated that lung spheroid cell derived exosomes (LSC-Exo) carry the parental cell’s ACE2 that are able to target lung, intercept SARS-CoV-2 entry, confer protection against SARS-CoV-2 infection. This LSC-Exo prophylaxis paradigm would not be limited by viral evolution, showing great potential for emerged SARS-CoV-2 variants, including those that are yet to emerge.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Lung, Epithelial Cell

DISEASE(S): Disease Free

SUBMITTER: Zhenzhen Wang  

LAB HEAD: Zhenzhen Wang

PROVIDER: PXD047542 | Pride | 2024-01-13

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
A1.xml Xml
HEK-Exo.raw Raw
ID102346_01_FSN20560_10061_042623.mzid.gz Mzid
ID102346_01_FSN20560_10061_042623.mzid_ID102346_01_FSN20560_10061_042623.MGF Mzid
ID102347_01_FSN20560_10061_042623.mzid.gz Mzid
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