Proteomics

Dataset Information

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Chemical translatome analysis in AML cells treated with different drug combinations


ABSTRACT: Our prior research has shown that AML with FLT3-ITD is particularly susceptible to the combination of FLT3 inhibitors and protein synthesis inhibitors when compared to FLT3-WT. In this study, we employed a click chemistry-based approach to quantify the alterations in the translatome under FLT3 inhibition and protein synthesis inhibition in AML cells.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Cell, Cell Suspension Culture

DISEASE(S): Acute Leukemia

SUBMITTER: Anskar Yu Hung Leung  

LAB HEAD: Prof. Anskar Yu-hung Leung

PROVIDER: PXD047567 | Pride | 2024-03-26

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
aml_AST_DA01.raw Raw
aml_AST_DA02.raw Raw
aml_AST_DA03.raw Raw
aml_AST_DA04.raw Raw
aml_AST_DA05.raw Raw
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