Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Trichomonas Vaginalis
SUBMITTER: Karel Harant
LAB HEAD: Jan Tachezy
PROVIDER: PXD047649 | Pride | 2024-06-16
REPOSITORIES: Pride
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Makki Abhijith A Kereïche Sami S Le Tien T Kučerová Jitka J Rada Petr P Žárský Vojtěch V Hrdý Ivan I Tachezy Jan J
BMC biology 20240603 1
<h4>Background</h4>Hydrogenosomes are a specific type of mitochondria that have adapted for life under anaerobiosis. Limited availability of oxygen has resulted in the loss of the membrane-associated respiratory chain, and consequently in the generation of minimal inner membrane potential (Δψ), and inefficient ATP synthesis via substrate-level phosphorylation. The changes in energy metabolism are directly linked with the organelle biogenesis. In mitochondria, proteins are imported across the out ...[more]