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Coxiella burnetii CBU2016 Proteomics

ABSTRACT: Proteomic analysis of Coxiella burnetii to understand the function of CBU2016

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Nichollas Scott

LAB HEAD: Hayley J Newton

PROVIDER: PXD047783 | Pride | 2024-10-17

REPOSITORIES: Pride

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			Action	DRS
	220801_DT-4664_1.raw	Raw
	220801_DT-4664_10.raw	Raw
	220801_DT-4664_11.raw	Raw
	220801_DT-4664_12.raw	Raw
	220801_DT-4664_2.raw	Raw

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Publications

Coxiella burnetii protein CBU2016 supports CCV expansion.

Thomas David R DR Garnish Sarah E SE Khoo Chen Ai CA Padmanabhan Bhavna B Scott Nichollas E NE Newton Hayley J HJ

Pathogens and disease 20240201

Coxiella burnetii is a globally distributed obligate intracellular pathogen. Although often asymptomatic, infections can cause acute Q fever with influenza-like symptoms and/or severe chronic Q fever. Coxiella burnetii develops a unique replicative niche within host cells called the Coxiella-containing vacuole (CCV), facilitated by the Dot/Icm type IV secretion system translocating a cohort of bacterial effector proteins into the host. The role of some effectors has been elucidated; however, the ...[more]

PMID: 39138067

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