Proteomics

Dataset Information

0

Mass spectrometry data of Platelet-rich plasma from 6 young and 6 elderly individuals


ABSTRACT: We prepared platelet-rich plasma from the blood of 6 young volunteers and 6 elderly volunteers, respectively, and removed 95% of high-abundance proteins, followed by mass spectrometry analysis.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Platelet, Platelet

SUBMITTER: Zhitong Jiang  

LAB HEAD: Kunfu Ouyang

PROVIDER: PXD050061 | Pride | 2024-04-24

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20240223_085422_20221014_Y_vs_O_1_6_Report_peptides.xls Xls
20240223_092500_20221014_Y_vs_O_1_6_Report.xls Xls
Nano_LC_MS_MS_Analysis_Parameters_and_Settings.xlsx Xlsx
O1.raw Raw
O2.raw Raw
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Publications

Platelet-Rich Plasma in Young and Elderly Humans Exhibits a Different Proteomic Profile.

Jiang Zhitong Z   Huang Can C   Guo Erliang E   Zhu Xiangbin X   Li Na N   Huang Yu Y   Wang Peihe P   Shan Hui H   Yin Yuxin Y   Wang Hong H   Huang Lei L   Han Zhen Z   Ouyang Kunfu K   Sun Lu L  

Journal of proteome research 20240415 5


As people age, their ability to resist injury and repair damage decreases significantly. Platelet-rich plasma (PRP) has demonstrated diverse therapeutic effects on tissue repair. However, the inconsistency of patient outcomes poses a challenge to the practical application of PRP in clinical practice. Furthermore, a comprehensive understanding of the specific impact of aging on PRP requires a systematic investigation. We derived PRP from 6 young volunteers and 6 elderly volunteers, respectively.  ...[more]

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