Homeoviscous adaptation in Escherichia coli
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ABSTRACT: All free-living microorganisms homeostatically maintain the fluidity of their membranes by adapting lipid composition to environmental temperatures. A quantitative description of how organisms maintain constant fluidity at all growth temperatures has not been achieved. By quantifying both enzymes and metabolic intermediates of the Escherichia coli fatty acid and phospholipid synthesis pathways, we discover how E. coli measures steady-state temperature and restores optimal membrane fluidity within a single generation after temperature shocks.
INSTRUMENT(S): 6410 Triple Quadrupole LC/MS
ORGANISM(S): Escherichia Coli
SUBMITTER: Gregory Bokinsky
LAB HEAD: Gregory Bokinsky
PROVIDER: PXD051802 | Pride | 2024-10-10
REPOSITORIES: Pride
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