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Homeoviscous adaptation in Escherichia coli

ABSTRACT: All free-living microorganisms homeostatically maintain the fluidity of their membranes by adapting lipid composition to environmental temperatures. A quantitative description of how organisms maintain constant fluidity at all growth temperatures has not been achieved. By quantifying both enzymes and metabolic intermediates of the Escherichia coli fatty acid and phospholipid synthesis pathways, we discover how E. coli measures steady-state temperature and restores optimal membrane fluidity within a single generation after temperature shocks.

INSTRUMENT(S): 6410 Triple Quadrupole LC/MS

ORGANISM(S): Escherichia Coli

SUBMITTER: Gregory Bokinsky

LAB HEAD: Gregory Bokinsky

PROVIDER: PXD051802 | Pride | 2024-10-10

REPOSITORIES: Pride

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			Action	DRS
	20210223_Analysis.zip	Other
	20210223_RAW.zip	Other
	20210707_Analysis.zip	Other
	20210707_RAW.zip	Other
	20220223_Analysis.zip	Other

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