Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Exploris 480
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cerebrospinal Fluid
DISEASE(S): Acute Leukemia
SUBMITTER: Ole Østergaard
LAB HEAD: Jesper Velgaard Olsen
PROVIDER: PXD052666 | Pride | 2024-10-16
REPOSITORIES: Pride
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12m_E_DDA_peptides.txt | Txt | |||
12m_E_DDA_proteinGroups.txt | Txt | |||
12m_M_DDA__proteinGroups.txt | Txt | |||
12m_M_DDA_peptides.txt | Txt | |||
12m_R_DDA_peptides.txt | Txt |
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Journal of proteome research 20241009 11
The cerebrospinal fluid (CSF) is a key matrix for discovery of biomarkers relevant for prognosis and the development of therapeutic targets in pediatric central nervous system malignancies. However, the wide range of protein concentrations and age-related differences in children makes such discoveries challenging. In addition, pediatric CSF samples are often sparse and first prioritized for clinical purposes. The present work focused on optimizing each step of the proteome analysis workflow to e ...[more]