Dataset Information
Analysis of extracellular vesicles from large granular lymphocytic leukemia cell lines
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive Plus
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Lymphocyte
DISEASE(S): T-cell Large Granular Lymphocyte Leukemia
SUBMITTER: 
Andreas Tholey
LAB HEAD: Andreas Tholey
PROVIDER: PXD053228 | Pride | 2024-10-17
REPOSITORIES: Pride
Dataset's files
Items per page: 1 - 5 of 8 |
Publications
Analysis of Cytotoxic Granules and Constitutively Produced Extracellular Vesicles from Large Granular Lymphocytic Leukemia Cell Lines.
Cells 20240806 16
<h4>Background</h4>Large granular lymphocyte leukemias (LGLLs) are rare lymphoproliferative malignancies caused by clonal expansion of granular lymphocytes. T-cell LGLL and natural killer (NK) cell LGLL are defined based on their cellular origin. Their clinical manifestation and pathophysiology vary depending on the subtype and include, e.g., neutropenia, anemia, recurrent infections, and autoimmunity. A limited number of available patient-derived cell lines are considered valuable tools to stud ...[more]
