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Identification of lysine sorbylation

ABSTRACT: We discovered that cellular uptake of sorbate, an FDA-approved and widely used food preservative, can induce lysine sorbylation (Ksor), a new posttranslational modification and epigenetic mark. Proteomics analysis identified over 20 histone sorbylation sites in cells and mouse liver as well as over 900 proteins in Raw264.7 cells as lysine sorbylation targets.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse)

TISSUE(S): Liver, Cell Culture, Macrophage

SUBMITTER: Yue Chen

LAB HEAD: Yue Chen

PROVIDER: PXD058007 | Pride | 2025-04-22

REPOSITORIES: pride

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			Action	DRS
	20210311_sorbic_liver_L11_gel1.raw	Raw
	20210311_sorbic_liver_L11_gel2.raw	Raw
	20210311_sorbic_liver_L11_gel3.raw	Raw
	20210311_sorbic_liver_L5_gel1.raw	Raw
	20210311_sorbic_liver_L5_gel2.raw	Raw

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