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Streptomyces coelicolor A3(2)

ABSTRACT: Analysis of the mutations responsible for ofloxacin resistance in Streptomyces coelicolor A3(2)

PROVIDER: PRJDB12293 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	DRR318613_1.fastq.gz	Fastqsanger.gz
	DRR318613_2.fastq.gz	Fastqsanger.gz
	DRR318614_1.fastq.gz	Fastqsanger.gz
	DRR318614_2.fastq.gz	Fastqsanger.gz
	DRR318615_1.fastq.gz	Fastqsanger.gz

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Streptomyces coelicolor A3(2) Timecourse Proteomics

Project description:Streptomyces coelicolor A3(2) shotgun proteomics. S. coelicolor A3(2) was fermented in GYM.

2022-03-23 | MSV000089111 | MassIVE

Streptomyces coelicolor A3(2)

Project description:Analysis of the mutations responsible for erythromycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2)

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Transcriptome profiles of Streptomyces coelicolor A3(2) wild type treated with kanamycin and iron

Project description:We determine genes that responsible for iron induced resistance to kanamycin in Streptomyces coelicolor. Iron acts as a inducing agent for resistance to bactericidal antibiotics with concentration dependent manner. Identification of iron-dependent differentially expressed genes in wild-type by RNA-seq identified more than 100 genes. This series encompasses the RNA-seq data of our study.

2022-03-10 | GSE168567 | GEO

Comparative genomic hybridization Streptomyces coelicolor A3(2) strains

Project description:The chromosomes of several widely used laboratory derivatives of Streptomyces coelicolor A3(2) were found to have 1.06 Mb inverted repeat sequences at their termini (i.e. long-terminal inverted repeats; L-TIRs), which are 50 times the length of the 22 kb TIRs of the sequenced S. coelicolor strain M145. The L-TIRs include 1005 annotated genes and increase the overall chromosome size to 9.7 Mb. The 1.06 Mb L-TIRs are the longest reported thus far for an actinomycete, and are proposed to represent the chromosomal state of the original soil isolate of S. coelicolor A3(2). S. coelicolor A3(2), M600 and J1501 possess L-TIRs, whereas approximately half the examined early mutants of A3(2) generated by ultraviolet (UV) or X-ray mutagenesis have truncated their TIRs to the 22 kb length. UV radiation was found to stimulate L-TIR truncation. Two copies of a transposase gene (SCO0020) flank 1.04 Mb of DNA in the right L-TIR, and recombination between them appears to generate strains containing short TIRs. This TIR reduction mechanism may represent a general strategy by which transposable elements can modulate the structure of chromosome ends. The presence of L-TIRs in certain S. coelicolor strains represents a major chromosomal alteration in strains previously thought to be genetically similar.

2005-07-21 | E-SMDB-2740 | biostudies-arrayexpress

Streptomyces coelicolor A3(2)

Project description:Streptomyces coelicolor A3(2) SigR regulon

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Genome plasticity in Streptomyces: identification of 1 Mb TIRs in the S. coelicolor A3(2) chromosome

2005-07-26 | GSE2994 | GEO

Fractionation of different lignocelullose by Streptomyces coelicolor A3(2) and production of secondary metabolites

Project description:The goal was to study the dfactionation of different lignocelullose (glucose, wheat bran, wheat straw) by Streptomyces coelicolor A3(2) and the corresponding production of secondary metabolites. This was performed by multi-omic experiment such as transcriptomic/metabolomic and leads to the production of new metabolites. For that, the strain Streptomyces coelicolor A3(2) was subjected to two carbon sources in triplicate (wheat bran and glucose as control). Enzymatic activities were studied at different times and the expression of CAZYmes was studied by transcriptomic in order to detect which enzymes are needed for each carbon source

2020-10-01 | E-MTAB-8971 | biostudies-arrayexpress

Streptomyces coelicolor A3(2) strain:ICSSB 1010

Project description:Streptomyces coelicolor A3(2) genome sequencing

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CGH of Streptomyces coelicolor versus S. lividans 66 and TK24

Project description:Comparative genomic hybridization analysis of Streptomyces coelicolor A3(2) versus Streptomyces lividans 66 and Streptomyces lividans TK24 using high density 105,000 x 60-mer ink-jet in situ synthesized arrays.

2011-10-01 | E-MAXD-58 | biostudies-arrayexpress

Genome plasticity in Streptomyces: identification of 1 Mb TIRs in the S. coelicolor A3(2) chromosome

2005-07-26 | E-GEOD-2994 | biostudies-arrayexpress