Project description:To establish a genomewide gene expression profile of OS-derived induced pluripotent stem cell lines (OS-iPSC): iG-292 and iSaos-2, against the parental cell lines, G-292 and Saos-2. OS cell lines were first reprogrammed into pluripotent state by retroviral transduction of OSKM. Six OS-iPSC clones and four parental OS cell lines were subjected to mRNA microarray analysis (Affymetrix Human PrimeView Chip).
Project description:Mantle Cell lymphoma (MCL) were treated with the BTK inhibitor 1mM CC-292 for 48h We used microarrays to uncover the mechanisms underlying CC-292 activity in Mantle Cell lymphoma (MCL)
