Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: RNA-seq analysis of germ cells derived from mouse chromosome substitution strains

PROVIDER: PRJDB3941 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	DRR035975_1.fastq.gz	Fastqsanger.gz
	DRR035975_2.fastq.gz	Fastqsanger.gz
	DRR035976_1.fastq.gz	Fastqsanger.gz
	DRR035976_2.fastq.gz	Fastqsanger.gz
	DRR035985_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 32

Similar Datasets

Mus musculus

Project description:Expression data from testes of the mouse X-chromosome substitution strains

| PRJNA218528 | ENA

Mus musculus

Project description:RNA-seq analysis of ES cell lines derived from mouse chromosome sibstitution strains

| PRJDB3393 | ENA

Mus musculus embryonic germ cell transcriptome

Project description:Identification of the mouse embryonic germ cell transcriptome

2015-08-13 | GSE70360 | GEO

Testis expression in Mus musculus domesticus WSB/EiJ x Mus musculus musculus PWD/PhJ F2 hybrids

Project description:To characterize the genetic basis of hybrid male sterility in detail, we used a systems genetics approach, integrating mapping of gene expression traits with sterility phenotypes and QTL. We measured genome-wide testis expression in 305 male F2s from a cross between wild-derived inbred strains of M. musculus musculus and M. m. domesticus. We identified several thousand cis- and trans-acting QTL contributing to expression variation (eQTL). Many trans eQTL cluster into eleven ‘hotspots,’ seven of which co-localize with QTL for sterility phenotypes identified in the cross. The number and clustering of trans eQTL - but not cis eQTL - were substantially lower when mapping was restricted to a ‘fertile’ subset of mice, providing evidence that trans eQTL hotspots are related to sterility. Functional annotation of transcripts with eQTL provides insights into the biological processes disrupted by sterility loci and guides prioritization of candidate genes. Using a conditional mapping approach, we identified eQTL dependent on interactions between loci, revealing a complex system of epistasis. Our results illuminate established patterns, including the role of the X chromosome in hybrid sterility.

2014-05-01 | GSE54089 | GEO

Mus musculus Stra8-deficient fetal ovary transcriptome

Project description:Identification of the mouse embryonic germ cell Stra8-/- transcriptome

2015-08-13 | GSE70359 | GEO

Mus musculus Dazl-deficient fetal ovary transcriptome

Project description:Identification of the mouse embryonic germ cell Dazl-/- transcriptome

2015-08-13 | GSE70358 | GEO

Widespread epistasis regulates glucose homeostasis and gene expression

Project description:Liver gene expression analysis in mouse chromosome substitution strains

2017-09-19 | GSE93591 | GEO

Mus musculus musculus

Project description:mouse chromosome 1 substitution population whole genome resequencing

| PRJNA298468 | ENA

Expression data from liver of male mouse at 10-week-old

Project description:To investigate mouse intersubspecific divergence of transcriptional regulation between C57BL/6J (B6) and Japanese wild-derived MSM/Ms strains, we performed transcriptome analysis by microarray on liver from B6 and MSM, and B6-ChrNMSM chromosome substitution strain panel, which carries MSM-derived chromosome or chromosomal segment on the B6 host.

2023-03-31 | GSE72825 | GEO

Mus musculus

Project description:ChIP-seq analysis of H3K4me1, H3K4me3 and H3K27me3 modification in testes of chromosome substitution strains.

| PRJDB2493 | ENA