Project description:The goal of this study was to investigate the differential gene expression between wild types and different nas-38 mutants during lethargus. Extremely prolonged lethargus in nas-38(ok3407) mutants and slightly shortened lethargus in nas-38(tm2655) was observed before.
Project description:MLS000408882-01 and MLS000573813-01 were identified through a cell based screen that measures the reactivation of an epigenetically silenced transgene. MLS000408882-01 and MLS000573813-01 shows selectivity for cancer vs. normal cells affecting both transcriptional patterns and cell viability in a cancer specific manner.
Project description:AST- and NAS-derived dopamine neurons were compared for their gene expression profiles after differentiation. Functional data was also collected in terms of neurophysiology.