Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Drosophila melanogaster

ABSTRACT: Single cell transcriptome atlas of Drosophila gastrula embryos

PROVIDER: PRJDB9523 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	DRR217309.fastq.gz	Fastqsanger.gz
	DRR217310.fastq.gz	Fastqsanger.gz

Items per page:

1 - 3 of 3

Similar Datasets

Drosophila melanogaster

Project description:Single cell RNA-seq of Drosophila gastrula by using 10x Chromium

| PRJDB11357 | ENA

Drosophila melanogaster

Project description:Single cell RNA-seq of Drosophila gastrula by using Fluidigm C1 HT

| PRJDB11328 | ENA

SILAC-based quantitative proteomic analysis of Drosophila gastrula stage embryos mutant for fibroblast growth factor signalin

Project description:Quantitative mass spectrometry-based proteomic analyses in combination with genetics provide powerful tools in developmental cell signaling research. Drosophila melanogaster is one of the most widely used genetic models for studying development and disease. Here we combined quantitative proteomics with genetic selection to determine global changes in the proteome upon depletion of the Heartless (Htl) Fibroblast-Growth Factor (FGF) receptor signaling in Drosophila embryos at the gastrula stage. We present a robust, single generation SILAC (stable isotope labeling with amino acids in cell culture) protocol for labeling proteins in early embryos and for the selection of homozygously mutant embryos at pre-gastrula stages using an independent genetic marker. Our analyses detected quantitative changes in the global proteome of htl mutant embryos during gastrulation. We identified distinct classes of down-regulated and up-regulated proteins and network analyses indicates functionally related groups of proteins in each class. In addition, we identified changes in the abundance of phosphopeptides. These data suggest that FGF signaling in the early embryo affects global changes in the abundance of metabolic, nucleoplasmic, cytoskeletal and transport proteins.

2021-09-09 | PXD016438 | Pride

Drosophila melanogaster

Project description:Organ-specific gene expression in single differentiating Drosophila embryos

| PRJNA310323 | ENA

Drosophila melanogaster

Project description:wounded versus nonwounded drosophila embryos

| PRJNA109001 | ENA

Drosophila melanogaster

Project description:Axon Guidance Study in Drosophila embryos

| PRJNA98601 | ENA

Drosophila melanogaster

Project description:Hi-C of early Drosophila melanogaster embryos