Novel pathways for ameliorating the fitness cost of gentamicin resistant small colony variants
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ABSTRACT: Small colony variants (SCVs) of the human pathogen Staphylococcus aureus are associated with persistent and recurrent infections. They are characterized by slow growth and can arise due to interrupted electron transport that consequently reduce membrane potential and thereby limit uptake of aminoglycosides (e.g. gentamicin). Here we have examined by which pathways the fitness cost of SCVs can be ameliorated.
PROVIDER: PRJEB15409 | ENA |
REPOSITORIES: ENA
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