Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Clostridium difficile ribotype 027 resequencing

ABSTRACT: Clostridium difficile ribotype 027 resequencing

PROVIDER: PRJEB2207 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	ERR025342_1.fastq.gz	Fastqsanger.gz
	ERR025342_2.fastq.gz	Fastqsanger.gz
	ERR025343_1.fastq.gz	Fastqsanger.gz
	ERR025343_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 313

Similar Datasets

Clostridium difficile ribotype 027 project

Project description:Clostridium difficile ribotype 027 project

| PRJEB2134 | ENA

Comparative genomic hybridization of Clostridium difficile strains to identify markers of different ribotypes

Project description:Clostridium difficile (C. difficile) strains belonging to PCR ribotype 027, PFGE type NAP1, REA type B1 and toxinotype III, termed NAP1/027, have been implicated in the increased frequency of outbreaks of Clostridium difficile-associated diarrhoea (CDAD) in North America and Europe. The NAP1/027 strains appears to be more virulent with an increased mortality and frequency of relapse. Current European C. difficile microarrays are designed to the first sequenced and annotated C. difficile complete genome - strain 630 (ribotype 12). A high density oligonucleotide microarray was designed to C. difficile 630 (CD630) sequence and extra probes corresponding to two PCR ribotypes O27 strains C. difficile R20291 and QCD-32g58 were also included. Comparative genomic hybridisation was used to identify markers of ribotype 027 strains and markers to identify CD630. Strains hybridised to the array included the most prevalent ribotypes found in the UK and Europe (106 and 001) as well as the emerging hypervirulent ribotype 078.

2010-07-01 | E-MTAB-162 | biostudies-arrayexpress

Clostridium difficile ribotype 078 resequencing

Project description:Clostridium difficile ribotype 078 resequencing

| PRJEB2103 | ENA

WGS of Clostridioides (Clostridium) difficile ribotype 027

Project description:Molecular characterization of an outbreak of Clostridioides (Clostridium) difficile ribotype 027

| PRJEB30088 | ENA

C. difficile Ribotype 027 Outbreak in Bern, Switzerland

Project description:C. difficile Ribotype 027 Outbreak in Bern, Switzerland

| PRJEB37809 | ENA

Clostridium difficile ribotype 017 project

Project description:Clostridium difficile ribotype 017 project

| PRJEB2105 | ENA

Tracing the spread of Clostridium difficile ribotype 027 in Germany

Project description:Tracing the spread of Clostridium difficile ribotype 027 in Germany based on bacterial genome sequences

| PRJEB9067 | ENA

Global transcriptional response of Clostridium difficile carrying the ϕCD38-2 prophage

Project description:We used RNA-seq to conduct a genome-wide transcriptomic analysis of the C. difficile strain R20291 carrying the newly introduced ϕCD38-2 prophage. A total of 39 bacterial genes were differentially expressed in the R20291 lysogen, 26 of them being downregulated. Several of the regulated genes encode transcriptional regulators and PTS subunits involved in glucose, fructose and glucitol/sorbitol uptake and metabolism. Also of note, the presence of ϕCD38-2 upregulated the expression of a group of regulatory genes located in phi-027, a resident prophage common to most ribotype 027 isolates. The most differentially expressed gene was the conserved phase-variable cell wall protein CwpV, which was upregulated by about 20-fold in the lysogen. This is the first study describing the global response of C. difficile to the presence of a newly introduced prophage.

2014-12-22 | GSE56818 | GEO

Clostridium difficile Ribotype Reference Genome Project

Project description:Clostridium difficile Ribotype Reference Genome Project

| PRJEB2101 | ENA

Global transcriptional response of Clostridium difficile carrying the M-OM-^UCD38-2 prophage

Project description:We used RNA-seq to conduct a genome-wide transcriptomic analysis of the C. difficile strain R20291 carrying the newly introduced M-OM-^UCD38-2 prophage. A total of 39 bacterial genes were differentially expressed in the R20291 lysogen, 26 of them being downregulated. Several of the regulated genes encode transcriptional regulators and PTS subunits involved in glucose, fructose and glucitol/sorbitol uptake and metabolism. Also of note, the presence of M-OM-^UCD38-2 upregulated the expression of a group of regulatory genes located in phi-027, a resident prophage common to most ribotype 027 isolates. The most differentially expressed gene was the conserved phase-variable cell wall protein CwpV, which was upregulated by about 20-fold in the lysogen. This is the first study describing the global response of C. difficile to the presence of a newly introduced prophage. Two strains (WT and lysogen) were subjected for RNA-seq analysis with two biological replicates each.

2014-12-22 | E-GEOD-56818 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data