Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Drosophila Y chromosome gene traffic

ABSTRACT: High rate of translocation-based gene birth on the Drosophila Y chromosome

PROVIDER: PRJEB22850 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR2163720_1.fastq.gz	Fastqsanger.gz
	ERR2163720_2.fastq.gz	Fastqsanger.gz
	ERR2163721_1.fastq.gz	Fastqsanger.gz
	ERR2163721_2.fastq.gz	Fastqsanger.gz
	ERR2163722_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 30

Similar Datasets

ERCC6L2 suppresses chromosome translocation

Project description:ERCC6L2 suppresses chromosome translocation

| PRJNA1184159 | ENA

The birth and death of microRNA genes in Drosophila

Project description:MicroRNAs (miRNAs) are small, endogenously expressed RNAs that regulate mRNAs post-transcriptionally. The class of miRNA genes, like other gene classes, should experience birth, death and persistence of its members. We carried out deep sequencing of miRNAs from three species of Drosophila, and obtained 107,000 sequences that map to no fewer than 300 loci that were not previously known. We observe a large class of miRNA genes that are evolutionarily young, with a rate of birth of 12 new genes per million years (Myr). Most of these new miRNAs originated from non-miRNA sequences. Among the new genes, we estimate that 96% disappeared quickly in the course of evolution; only 4% of new miRNA genes were retained by natural selection. Furthermore, only 60% of these retained genes became integrated into the transcriptome in the long run (60 Myr). This small fraction (2.5%) of surviving miRNAs may later on become moderately or highly expressed. Our results suggest that there is a high birth rate of new miRNA genes, accompanied by a comparably high death rate. The estimated net gain of long-lived miRNA genes, which is not strongly affected by either the depth or the breadth (number of tissues) of sequencing, is 0.3 genes per Myr in Drosophila Keywords: 454 microRNA deep sequencing

2008-02-14 | GSE10515 | GEO

Drosophila melanogaster 2nd chromosome substitution lines

Project description:Transcriptional profiling of Drosophila melanogaster 2nd chromosome substitution lines; Background chromosomes are identical across lines; 2nd chromosomes are different across line and can be homozygous or heterozygous within each line Keywords: Natural variation

2010-05-06 | GSE12191 | GEO

The birth and death of microRNA genes in Drosophila

2008-02-14 | E-GEOD-10515 | biostudies-arrayexpress

Factor cooperation for chromosome discrimination in Drosophila

Project description:Factor cooperation for chromosome discrimination in Drosophila

| PRJNA490090 | ENA

Mitochondrial - Y Chromosome Epistasis in Drosophila melanogaster

Project description:Mitochondrial - Y Chromosome Epistasis in Drosophila melanogaster

| PRJNA649569 | ENA

Gene expression variation in Y-chromosome substitution lines of Drosophila melanogaster

Project description:These arrays were done in the context of a study to probe gene expression variation across Y-chromosome substitution lines of Drosophila melanogaster Keywords: polymorphism, evolution, chromosome substitution

2008-04-30 | GSE9457 | GEO

Mitochondrial - Y Chromosome Epistasis in Drosophila melanogaster

Project description:We generate 36 otherwise isogenic Drosophila melanogaster strains differing only in the geographical origin of their mitochondrial genome and Y chromosome to experimentally examine the effects of the uniparentaly inherited parts of the genome, as well as their interaction, in males. We assay gene expression through RNA-sequencing and detect an important role for both mitochondrial and Y-linked genes, as well as extensive mitochondrial-Y chromosome epistasis.

2020-07-30 | GSE155395 | GEO

Divergent evolutionary strategies for selective sex chromosome regulation in Drosophila

Project description:The dosage compensation complex (DCC) of Drosophila identifies its X chromosomal binding sites with exquisite selectivity. The principles that assure this vital targeting are known from the D. melanogaster model: DCC-intrinsic specificity of DNA binding, cooperativity with the CLAMP protein, and non-coding roX2 RNA transcribed from the X chromosome. We found that in D. virilis, a species separated from melanogaster by 40 million years of evolution, all principles are active, but contribute differently to X-specificity. In melanogaster, the DCC subunit MSL2 evolved intrinsic DNA-binding selectivity for rare PionX sites, which mark the X chromosome. In virilis, PionX sites are abundant and not X-enriched. Accordingly, MSL2 lacks specific recognition. Here, roX2 RNA plays a more instructive role, counteracting a non-productive interaction of CLAMP and modulating DCC binding selectivity. Remarkably, roX2 triggers a low-diffusion chromatin binding mode characteristic of DCC. Evidently, X-specific regulation is achieved by divergent evolution of similar components.

2021-06-23 | PXD023747 | Pride

Mitotic chromosome scaffold

Project description:Quantitative proteomics analysis of mitotic chromosome scaffold based on SILAC

2018-10-07 | PXD007269 | JPOST Repository