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Expression profiling of DDX3X and DDX54 knockdown in MCF7 cells

ABSTRACT: Expression profiling of DDX3X and DDX54 knockdown in MCF7 cells

PROVIDER: PRJEB23554 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR2200170_1.fastq.gz	Fastqsanger.gz
	ERR2200170_2.fastq.gz	Fastqsanger.gz
	ERR2200171_1.fastq.gz	Fastqsanger.gz
	ERR2200171_2.fastq.gz	Fastqsanger.gz
	ERR2200162_1.fastq.gz	Fastqsanger.gz

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Expression profiling of DDX3X and DDX54 knockdown in MCF7 cells

Project description:We performed RNA-seq to observe the gene expression changes in cells following siRNA-mediated knockdown of DDX3X and DDX54 RNA helicases in human breast cancer MCF7 cells. Two siRNAs were used to target each RNA helicase and scramble siRNA-treated MCF7 cells were used as controls.

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MCF7 cells with LIFR knockdown

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Inhibiting DDX3X triggers tumor-intrinsic type I interferon response and enhances anti-tumor immunity

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