Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Microbial Eukaryotes of Lagoons of the Solomon Islands

PROVIDER: PRJEB24428 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR2248482_1.fastq.gz	Fastqsanger.gz
	ERR2248482_2.fastq.gz	Fastqsanger.gz
	ERR2248483_1.fastq.gz	Fastqsanger.gz
	ERR2248483_2.fastq.gz	Fastqsanger.gz
	ERR2248484_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

aquatic metagenome

Project description:Protists in lagoons of the Solomon Islands

| PRJNA336325 | ENA

Project description:Zosterops Solomon Islands RAD-seq

| PRJNA602944 | ENA

Project description:Solomon Islands White-eye UCE reads

| PRJNA627899 | ENA

marine sediment metagenome

Project description:Microbial eukaryotes

| PRJNA244592 | ENA

Chlamydia trachomatis

Project description:Genome sequencing and assembly of ocular Chlamydia trachomatis isolates from the Solomon Islands

| PRJNA328474 | ENA

CpG islands recruit a histone H3 lysine 36 demethylase [Illumina sequencing data]

Project description:Eukaryotic gene expression profiles are largely defined by transcription factors that recognize specific DNA sequences in gene regulatory regions and impact RNA polymerase recruitment and transcription. In addition to specific core promoter regulatory elements, up to 70% of genes in higher eukaryotes are also characterized by an overrepresentation of cytosine/guanine base pairs (CpGs) surrounding promoters and gene regulatory units. These features, called CpG islands, were identified over twenty years ago but there remains little mechanistic evidence to suggest how these enigmatic elements contribute to promoter function, with the exception that they are refractory to epigenetic silencing by DNA methylation. Here we uncover a role for CpG islands in buffering gene regulatory elements from repressive histone H3 lysine 36 methylation by directly recruiting the H3K36 specific lysine demethylase enzyme KDM2A. KDM2A is recruited to CpG islands by a zinc finger CxxC (ZF-CxxC) domain that specifically recognizes CpG DNA and is blocked by DNA methylation. This capacity to sense the epigenetic methylation state of DNA constrains KDM2A to non-methylated CpG islands. Importantly, these observations suggest CpG islands may function to delineate gene regulatory elements from bulk chromatin by recruiting factors that create unique chromatin architecture. This study provides information about binding of lysine demethylase enzyme KDM2A in mouse embryonic stem cells.

2010-04-27 | E-GEOD-18588 | biostudies-arrayexpress

marine metagenome

Project description:Microbial eukaryotes Metagenome

| PRJNA241472 | ENA

CpG islands recruit a histone H3 lysine 36 demethylase [Illumina sequencing data]

2010-04-27 | GSE18588 | GEO

Project description:Microbial eukaryotes from Arctic

| PRJNA596339 | ENA

Project description:Microbial eukaryotes Genome sequencing

| PRJNA574242 | ENA