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Microbial community adaptability to altered temperature conditions

ABSTRACT: Microbial community adaptability to altered temperature conditions influences prospect for optimization in anaerobic digestion

PROVIDER: PRJEB24500 | ENA |

REPOSITORIES: ENA

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Project description:Prospect

| PRJNA817603 | ENA

Macrophage specific Mafb deficiency effects brown adipose tissue's cold adaptability

Project description:Macrophage specific Mafb deficiency effects brown adipose tissue's cold adaptability

| PRJNA935942 | ENA

Ecological Adaptability and Response Mechanism to Salt Stress of Wild Apocynum venetum

Project description:We selected wild A. venetum of four distributed regions (jinta county, minqin county, hangjinqi and baicheng) as the test materials in the study. Based on the study of community composition, population genetic diversity and soil environmental properties of wild A. venetum, physiological characteristics, transcriptomics and proteomics analysis of A. venetum under salt stress, and key regulatory proteins and genes of A. venetum salt tolerance were measured and identified to reveal the ecological adaptability of wild A. venetum and underlying mechanisms in response to salt stress. The study is beneficial to promote the protection and rational development and utilization of germplasm resources of wild A. venetum, and is of great significance to the development of national pharmacology and the construction of ecological civilization in China.

2024-04-09 | GSE229255 | GEO

Project description:Meta-prOSpEcT

| PRJNA803614 | ENA

Loss of ARNT Impair Adaptability of Muscular Exercise in Aged Mice

Project description:The adaptation of regimented exercise in skeletal muscle including muscular hypertrophy and enhanced strength decline significantly with aging. Transcriptome analysis following RNA sequencing reveals extensive activation of hypoxia-related genes in young exercised mice versus the sedentary, but absent in aged exercised mice. Particularly, less expression of aryl hydrocarbon receptor translocator (ARNT) was observed in response to exercise in aged mice. Young mice underwent skeletal muscle-specific knockout of ARNT (ARNT mKO) obtain deficient benefit from exercise resembling the aged mice. The deletion of ARNT associated with decreased expression of Notch1 intracellular domain(N1ICD) impair muscle hypertrophy and regeneration. Administration of ML228, a systematic agonist of ARNT, rescued skeletal muscle adaptabilities in old mice, which was suppressed by administrating N1ICD inhibitor(DAPT). These results suggest that the loss of skeletal muscle ARNT is partially responsible for diminished response to exercise in aging and activation of hypoxia signaling holds promise for rescuing the adaptability in aged muscle.

2021-12-31 | GSE155937 | GEO

Loss of ARNT Impair Adaptability of Muscular Exercise in Aged Mice

Project description:Loss of ARNT Impair Adaptability of Muscular Exercise in Aged Mice

| PRJNA656121 | ENA

Fermentation conditions

Project description:Systematic optimization of fermentation conditions for in vitro fermentations with fecal inocula

| PRJEB58105 | ENA

Ecological Adaptability and Response Mechanism to Salt Stress of Wild Apocynum venetum

Project description:Ecological Adaptability and Response Mechanism to Salt Stress of Wild Apocynum venetum

| PRJNA953652 | ENA

Grape Flavonoid Evolution and Composition Under Altered Light and Temperature Conditions in Cabernet Sauvignon (Vitis vinifera L.).

Project description:The evolution of flavonoids under altered temperature and light conditions in the fruit zone was followed in Cabernet Sauvignon (Vitis vinifera L.) grapes during ripening. The study was conducted over two consecutive seasons in 2010/2011 and 2011/2012 comprising two main treatments in which the light quantity was manipulated in the bunch zone: (1) standard (STD) with no lateral shoot or leaf removal and (2) leaf removal west (LRW) treatment with leaf removal on the western side of the bunch zone. Furthermore, the light quality was altered by installing ultraviolet B-suppression sheets within the bunch zone in both seasons. Tannin evolution was dependent on the prevailing light quality/quantity and temperatures during berry development in a particular season. Grape seed tannin accumulation coincided with seed development and commenced at the early stages of berry development. Seed proanthocyanidin composition was not influenced by the treatments. The largest impact on proanthocyanidin accumulation and structure in the skin was due to seasonal variations highlighting the complex interaction between light quality and/or quantity across the two growing seasons and eventually the complex interaction with temperature. Flavonol accumulation was significantly influenced by the light quality, which is known to be the main abiotic driver of flavonol biosynthesis regulation. Anthocyanin concentration and content were largely dependent on the temperature and light quality in a particular season. Anthocyanin composition was altered by the season rather than the treatment.

| S-EPMC6874162 | biostudies-literature

Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies

Project description:The objective of this expanded access program is to provide ulixertinib (BVD-523) for compassionate use in advanced cancer patients with MAPK pathway-altered solid tumor(s), including but not limited to KRAS, NRAS, HRAS, BRAF, MEK, and ERK mutations who have incomplete response to or have exhausted available therapies. Ulixertinib is available for treatment as monotherapy or in combination with other clinically tolerable agent(s), conditionally approved by the drug manufacturer.

| 2352905 | ecrin-mdr-crc

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