Project description:In Mycobacterium tuberculosis, the efflux pump, EfpA, plays an essential but uncharacterised role in its physiology and antibiotic tolerance. In this study, an ATc-inducible CRISPR interference (CRISPRi) system was introduced into M. tuberculosis to knock-down the expression of efpA and determine any subsequent effects on the organism. As part of the study, microarray experiments were performed to determine any changes in gene expression caused by efpA repression M. tuberculosis by comparing the transcriptomic profile between ATc-induced efpA knock-down cultures to that of efpA knock-down cultures without ATc-induction.

2024-06-19 | E-MTAB-13755 | biostudies-arrayexpress

Transcriptome sequencing of SLC2A10 knock-down VSMCs

Project description:Transcriptome sequencing of SLC2A10 knock-down VSMCs

| PRJNA786533 | ENA

MEF2C knock-down in Human Skeletal Myoblasts

Project description:MEF2C knock-down in Human Skeletal Myoblasts

| PRJNA525423 | ENA