Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Transcriptomic analysis of Faustovirus E12 during its replicative cycle on Vermamoeba vermiformis

PROVIDER: PRJEB28059 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR2724030_1.fastq.gz	Fastqsanger.gz
	ERR2724030_2.fastq.gz	Fastqsanger.gz
	ERR2724031_1.fastq.gz	Fastqsanger.gz
	ERR2724031_2.fastq.gz	Fastqsanger.gz
	ERR2724032_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 30

Similar Datasets

Vermamoeba vermiformis strain:CDC-19 | isolate:ATCC 50237

Project description:Vermamoeba vermiformis CDC-19 genome sequencing and assembly

| PRJNA1128894 | ENA

Project description:Hybrid genome sequencing of Vermamoeba vermiformis and its endosymbiont Vermiphilus pyriformis

| PRJNA720556 | ENA

Clandestinovirus: a giant virus with chromatin proteins and a potential to manipulate the cell cycle of its host Vermamoeba vermiformis

Project description:Clandestinovirus: a giant virus with chromatin proteins and a potential to manipulate the cell cycle of its host Vermamoeba vermiformis

| PRJEB45082 | ENA

Transcriptomic study of C4-2 prostate cancer cells under the treatment of direct HSF1 inhibitor DTHIB (E12)

Project description:This is a RNA-Seq analysis aiming to study the transcriptomic changes of C4-2 prostate cancer cells induced by HSF1 inhibitor DTHIB (E12)

2021-01-01 | GSE155248 | GEO

Lomanotus vermiformis

Project description:Lomanotus vermiformis

| PRJNA1067608 | ENA

RNA-seq of mice genital ridges from males and females at embryonic days E11 and E12

Project description:The aim of the study was to identify differentially expressed genes, isoforms and AS modifications accompanying Gonadal Sex Determination in mice. We performed a Rna-Seq analysis of XX and XY gonads during sex determination on embryonic days 11 (E11) and 12 (E12). RNA-seq libraries were prepared from grouped gonads from E11 and E12 males and females. The cDNA libraries were sequenced using a HiSeq2500 v4 chemistry system

2019-02-21 | E-MTAB-7656 | biostudies-arrayexpress

Using single-cell RNA-Seq for unbiased analysis of developmental hierarchies (scRNA-Seq of BM lineage-negative Sca1+ CD117+ CD150+CD48-cells)

Project description:Hematopoietic stem cell metabolic requirements change with their cell cycle activity. However, the underlying role of mitochondria remain ill-defined. The goal of our study is to investigate how hematopoietic stem cells use mitochondria during cell division to control their fate and self-renewal activity. We found that after mitochondrial activation with replication, HSC irreversibly remodel the mitochondrial network and this network is not repaired after HSC re-entry into quiescence. HSC keep and accumulate dysfunctional mitochondria through asymmetric segregation during active division. Single cell RNA seq and bioinformatic analysis are used to characterize hematopoietic stem cell functions before and after replicative stress to uncover novel key drivers that limit hematopoietic stem cell self-renewal after replicative stress.

2019-12-05 | GSE141472 | GEO

The lysine demethylase KDM4A controls the cell-cycle expression of replicative canonical histone genes

Project description:Chromatin modulation provides a key checkpoint for controlling cell cycle regulated gene networks. The replicative canonical histone genes are one such gene family under tight regulation during cell division. These genes are most highly expressed during S phase when histones are needed to chromatinize the new DNA template. While this fact has been known for a while, limited knowledge exists about the specific chromatin regulators controlling their temporal expression during cell cycle. Since histones and their associated mutations are emerging as major players in diseases such as cancer, identifying the chromatin factors modulating their expression is critical. The histone lysine tri-demethylase KDM4A is regulated over cell cycle and plays a direct role in DNA replication timing, site-specific rereplication, and DNA amplifications during S phase. Here, we establish an unappreciated role for the catalytically active KDM4A in directly regulating canonical replicative histone gene networks during cell cycle. Of interest, we further demonstrate that KDM4A interacts with proteins controlling histone expression and RNA processing. Together, this study provides a new function for KDM4A in modulating canonical histone gene expression.

2021-10-27 | GSE154684 | GEO

Regulation of Lipids is Central to Replicative Senescence

Project description:Cellular replicative senescence, a state of permanent cell-cycle arrest that occurs following an extended period of cell division in culture, has been linked to organismal aging, tissue repair and tumorigenesis. In this study, we comparatively investigated the global lipid profiles and mRNA content of proliferating and senescent-state BJ fibroblast cells. We found that both the expression levels of lipid-regulating genes, as well as the abundance of specific lipid families, are actively regulated. We further found that 19 polyunsaturated triacylglycerol species showed the most prominent changes during replicative senescence. We argue that diversion of polyunsaturated fatty acids to glycerolipid biosynthesis could be responsible for the accumulation of specific triacylglycerols. This, in turn, could be one of the cellular mechanisms to prevent lipotoxicity under increased oxidative stress conditions observed during replicative senescence. Collectively, our results place regulation of specific lipid species to a central role during replicative senescence.

2017-03-31 | GSE94280 | GEO

Genome-wide Analysis of Re-replication Reveals Inhibitory Controls that Target Multiple Stages of Replication Initiation

Project description:DNA replication must be tightly controlled during each cell cycle to prevent unscheduled replication and ensure proper genome maintenance. The currently known controls that prevent re-replication act redundantly to inhibit pre-Replicative Complex (pre-RC) assembly outside of the G1 phase of the cell cycle. We have analyzed the effects of re-replication on the S. cerevisiae genome using a combination of Comparitive Genomic Hybridization (CGH) of re-replicating strains and Genome-Wide Location Analysis of pre-RC components. These data indicate which sites in the genome assemble pre-RCs under re-replication conditions, which sites undergo re-initiation and the extent of re-replication. Keywords: comparative genomic hybridization, ChIP-chip, re-replication, DNA replication, pre-RC

2006-03-20 | GSE4487 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data