Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Holobiont of Baikal sponges

ABSTRACT: disease-associated holobiont of Lubomirskia baicalensis sponges

PROVIDER: PRJEB28162 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR2732911_1.fastq.gz	Fastqsanger.gz
	ERR2732911_2.fastq.gz	Fastqsanger.gz
	ERR2732973_1.fastq.gz	Fastqsanger.gz
	ERR2732973_2.fastq.gz	Fastqsanger.gz
	ERR2732993_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 10

Similar Datasets

freshwater metagenome

Project description:disease-associated holobiont of Lubomirskia baicalensis sponges

| PRJNA480194 | ENA

Sponge symbiotic bacterial communities metagenome

Project description:Screening of disease-associated microbiomes of Lubomirskia baicalensis sponges

| PRJNA480187 | ENA

Lubomirskia baikalensis

Project description:Lubomirskia baicalensis overview

| PRJNA503501 | ENA

Baikal sponges

Project description:Investigation of endemic baikalian sponge microbiome

| PRJEB28717 | ENA

Trichodesmium holobiont

Project description:Trichodesmium holobiont metaranscriptome

| PRJNA450995 | ENA

coral holobiont

Project description:coral holobiont Transcriptome

| PRJNA559028 | ENA

Screening and validation of lncRNAs and circRNAs as miRNA sponges [siRNA, miRNA-2_0]

Project description:Intensive research in past two decades has uncovered the presence and importance of noncoding RNAs (ncRNAs), which includes microRNAs (miRs) and long ncRNAs (lncRNAs). These two classes of ncRNAs interact to a certain extent, as some lncRNAs bind to miRs to sequester them. Such lncRNAs are collectively called 'competing endogenous RNAs' or 'miRNA sponges'. In this study, we screened for lncRNAs that may act as miRNA sponges using the publicly available data sets and databases. To uncover the roles of miRNA sponges, loss-of-function experiments were conducted, which revealed the biological roles as miRNA sponges. LINC00324 is important for the cell survival by binding to miR-615-5p leading to the de-repression of its target BTG2 LOC400043 controls several biological functions via sequestering miR-28-3p and miR-96-5p, thereby changing the expressions of transcriptional regulators. Finally, we also screened for circular RNAs (circRNAs) that may function as miRNA sponges. The results were negative at least for the selected circRNAs in this study. In conclusion, miRNA sponges can be identified by applying a series of bioinformatics techniques and validated with biological experiments.

2016-07-06 | GSE73689 | GEO

Trichodesmium holobiont

Project description:Trichodesmium holobiont Raw sequence reads

| PRJNA435427 | ENA

Screening and validation of lncRNAs and circRNAs as miRNA sponges [cell lines, miRNA-2_0]

2016-07-06 | GSE73690 | GEO

Coral holobiont

Project description:Coral holobiont Transcriptome or Gene expression

| PRJNA255491 | ENA