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Annona muricata complete genome

ABSTRACT: The genome of Annona muricata (the soursop)

PROVIDER: PRJEB30626 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR3334070_1.fastq.gz	Fastqsanger.gz
	ERR3334070_2.fastq.gz	Fastqsanger.gz
	ERR3334080_1.fastq.gz	Fastqsanger.gz
	ERR3334080_2.fastq.gz	Fastqsanger.gz
	ERR3334081_1.fastq.gz	Fastqsanger.gz

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Annona muricata

Project description:Annona muricata overview

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Annona muricata

Project description:Annona muricata Linn. chloroplast Genome sequencing

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Annona muricata

Project description:Annona muricata Genome sequencing and assembly

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Aqueous and DMSO extracts from Annona muricata leaves protect from ferroptosis to both HT-1080 fibrosarcoma cells and HMEC-1 endothelial cells.

Project description:Graviola (Annona muricata) is a tropical plant with many traditional ethnobotanic uses and pharmacologic applications. A metabolomic study of both aqueous and DMSO extracts from Annona muricata leaves recently allowed us to identify dozens of bioactive compounds. In the present study, we use a proteomic study to reveal new bioactivities of these leave extracts on both conditioned media and extracts of HT-1080 fibrosarcoma treated cells. Our results reveal the complete sets of deregulated proteins after treatment with aqueous and DMSO extracts from An-nona muricata leaves. Functional enrichment analysis of proteomic data suggests deregulation of cell cycle and iron metabolism, which are experimentally validated. Additional experimental data reveal that these extracts protect from ferroptosis to both HT-1080 fibrosarcoma cells and HMEC-1 endothelial cells.

2023-10-24 | PXD042354 | Pride

Effect of Annona Muricata Leaves on Colorectal Cancer Patients and Colorectal Cancer Cells

Project description:Annona muricata L., include the leaves, is found to contain biologically active Annonaceous acetogenins and plant polyphenols that are important components of human diet and a number of them are considered to have chemopreventive and therapeutic properties against cancer. To confirm previous findings in in vitro, animal study and traditionally use, a human, ex vivo and in vitro studies were conducted to evaluate the effects of consecutive ingestion of A. muricata leaves extract for eight weeks.

| 2189667 | ecrin-mdr-crc

Anticancer compounds from Annona muricata target protein glycosylation processes in lung cancer cells_proteomics

Project description:Treatment of A549 lung cancer cells with novel cytotoxic compounds isolated from Annona muricata. Mass spectrometry data was obtained for proteomics and glycoproteomics.

2022-10-28 | MSV000090613 | MassIVE

Anticancer compounds from Annona muricata target protein glycosylation processes in lung cancer cells_glycoproteomics

Project description:Treatment of A549 lung cancer cells with novel cytotoxic compounds isolated from Annona muricata. Mass spectrometry data was obtained for proteomics and glycoproteomics.

2022-10-28 | MSV000090612 | MassIVE

Endocladia muricata

Project description:Endocladia muricata

| PRJNA894599 | ENA

Annona montana

Project description:Annona montana Genome sequencing

| PRJNA497754 | ENA

The complete chloroplast genome of <i>Annona muricata</i> L.: a tropical fruit with important medicinal properties.

Project description:Annona muricata L. (A. muricata) is an important tropical fruit and medicinal plant. It is one of the easily found plants used traditionally in treating cancer. In many tropical countries, especially in Southeast Asia, A. muricata is popular for its edible fruit and medicinal merits. In this study, the complete chloroplast genome of A. muricata was sequenced, assembled, and annotated. The chloroplast genome of A. muricata was found to be a double strand ring structure with the size of 196,038 bp that consists of four regions: a large single-copy region of 75,339 bp, a small single-copy region of 3105 bp, and two inverted repeat regions of 58,797 bp. The GC content of the whole chloroplast genome was 39.92%. It was found that 111 protein-coding genes, one Pseudogene, 38 tRNA genes, and eight rRNA genes were annotated in the chloroplast genome, and the total number of genes was 158. DNA sequences of the chloroplast genomes of 19 species which belonged to three families of Magnoliales order were analyzed and a phylogenetic tree was constructed. The result indicated that A. muricata, Annona cherimola, Uvaria macrophylla, Greenwayodendron suaveolens, and Chieniodendron hainanense had a close phylogenetic relationship. The findings also provided abundant basic data for the genomics study of A. muricata.

| S-EPMC7781942 | biostudies-literature

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