Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Eukaryotic microbial community German Bight March - Oktober 2016

ABSTRACT: 18s rDNA reads of eukaryotic microbial community in the German Bight

PROVIDER: PRJEB32095 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

eukaryotic aquatic metagenome

Project description:Eukaryotic 18S metabarcoding

| PRJDB15289 | ENA

Wheat straw eukaryotic microbial community

Project description:Wheat straw eukaryotic microbial community 18S gene amplicon Raw sequence reads

| PRJNA1232993 | ENA

DNA methylome of German Shepherd

Project description:Using WGBS we investigated blood DNA methylation profiles of German Shepherd and determined putative regulatory elements (unmethlated regions (UMRs) and lowly methylated regions (LMRs).

2020-02-04 | GSE136348 | GEO

Crac analysis of the Bud22 ribosome biogenesis factor

Project description:Bud22 binds to the 5´domain of 18S rRNA and U14 snoRNA Grant Number: BA 2316/2-1 German Research Foundation (DFG) Grantee: Jochen,,Baßler

2023-04-30 | GSE214203 | GEO

Transcriptome responses to defined insecticide selection pressures in the German cockroach

Project description:Purpose: Next-generation transcriptome sequencing was done to understand host and eukaryotic microbiome changes in gene expression in association with defined insecticide selection pressures. The specific goal of this research was to understand whole-body physiological responses in German cockroaches and associated microbiota, at the metatranscriptome level, to defined insecticide selection pressures. Methods: We used the insecticide indoxacarb as the selecting insecticide, which is an important bait active ingredient for cockroach control. Six generations of selection with indoxacarb bait produced a strain with substantial (>20x) resistance relative to inbred control lines originating from the same parental stock. Results: Metatranscriptome sequencing revealed 1123 significantly differentially expressed genes in > two of three statistical models (81 upregulated and 1042 downregulated; FDR p<0.001; log2FC of +/- 1). The majority of upreglated genes were from the host cockroach while the majority of downregulated genes were from associated viruses and the eukaryotic microbiome. Conclusions: We show here significant impacts by insecticide selection on not only host stress-respnses like detoxification, but also on clearace of microbial parasites, pathogens, commensals and/or symbionts.

2021-12-07 | GSE188950 | GEO

Southern Ocean Eukaryotic Diversity

Project description:Samples of eukaryotic plankton sequenced at the V4 rDNA region.

| PRJEB25232 | ENA

Haima cold seep sediment eukaryotic 18S samples

Project description:Haima cold seep sediment eukaryotic 18S samples Raw sequence reads

| PRJNA1048635 | ENA

Project description:18S rDNA

| PRJNA1132392 | ENA

UtpA and UtpB chaperone nascent pre-ribosomal RNA and the U3 snoRNP to initiate eukaryotic ribosome assembly

Project description:Early eukaryotic ribosome biogenesis involves large multi-protein complexes, which co-transcriptionally associate with pre-ribosomal RNA to form the small subunit processome. The precise mechanisms by which two of the largest multi-protein complexes – UtpA and UtpB – interact with nascent pre-ribosomal RNA have so far been poorly understood. We have combined biochemical and structural biology approaches with ensembles of RNA-protein cross-linking to elucidate the essential function of both complexes. Here we show that UtpA contains a large composite RNA binding site and captures the 5´ end of pre-ribosomal RNA. UtpB forms an extended structure that binds early pre-ribosomal intermediates in close proximity to key architectural sites such as an RNA duplex formed by the 5´ ETS and U3 snoRNA as well as the 3´ boundary of 18S rRNA. Both complexes therefore act as vital RNA chaperones to initiate eukaryotic ribosome assembly.

2016-09-21 | GSE79950 | GEO

Visualize and quantify rDNA instabilities in mammalian cells and mouse models

Project description:Ribosomal DNA (rDNA) encodes the 18S, 5.8S, and 28S RNA components of ribosomes, accounting for up to 70% of cellular transcription. Despite its central role in cellular function and known association with cancer and aging, quantifying rDNA instability in mammals remains challenging due to its repetitive organization and inherent heterogeneity. In this study, we developed murine rDNA FISH probes and genomic tools tailored for laboratory strains. The results confirmed the locations of rDNA clusters, uncovered marked inter-/intra-strain and inter-cell heterogeneity at rDNA loci in inbred mice and unstressed cells, and identified sources of spontaneous, replication-associated DNA double-strand breaks within rDNA. Focused mini-screens using DNA repair-deficient cells uncovered distinct contributions of homologous recombination, non-homologous end-joining, and the ATM-mediated DNA damage response in safeguarding rDNA stability. Together, these findings and tools provide a robust framework for assessing rDNA instability in mammalian cells and animal models with applications in aging and cancer research.

2025-12-18 | GSE297694 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data