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MRNA-seq of Arabidopsis mutants : pol2a-12, cmt3-11, pol2a-12 cmt3-11, fas2-4, pol2a-12 atxr5/6

ABSTRACT: mRNA-seq of Arabidopsis mutants : pol2a-12, cmt3-11, pol2a-12 cmt3-11, fas2-4, pol2a-12 atxr5/6

PROVIDER: PRJEB38704 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR4194070.fastq.gz	Fastqsanger.gz
	ERR4194080.fastq.gz	Fastqsanger.gz
	ERR4194071.fastq.gz	Fastqsanger.gz
	ERR4194081.fastq.gz	Fastqsanger.gz
	ERR4194072.fastq.gz	Fastqsanger.gz

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mRNA-seq of Arabidopsis mutants : pol2a-12, cmt3-11, pol2a-12 cmt3-11, fas2-4, pol2a-12 atxr5/6

Project description:DNA replication requires the faithful propagation of both genetic and epigenetic information. There is evidence that DNA polymerases play a role in transcriptional silencing, but the extent of their contribution and how it relates to heterochromatin maintenance is unclear. To get a better understanding of the role of POL2A, the catalytic subunit of the DNA polymerase epsilon, into maintaining heterochromatin silencing, we performed mRNA-seq on Arabidopsis plants carrying a new hypomorphic pol2a mutation. We deepened our analysis by profiling transcriptomes of other silencing mutants or combinations of pol2a with other mutations.

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