Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq of human melanoma cell line A375m2 treated with SB202190 OR BIRB796 against DMSO-treated controls

ABSTRACT: RNA-seq of human melanoma cell line A375m2 treated with SB202190 OR BIRB796 against DMSO-treated controls

PROVIDER: PRJEB39122 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR4299880_1.fastq.gz	Fastqsanger.gz
	ERR4299880_2.fastq.gz	Fastqsanger.gz
	ERR4299881_1.fastq.gz	Fastqsanger.gz
	ERR4299881_2.fastq.gz	Fastqsanger.gz
	ERR4299882_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

RNA-seq of human melanoma cell line A375m2 treated with SB202190 OR BIRB796 against DMSO-treated controls

Project description:Melanoma cells can switch between a more differentiated, proliferative phenotype and a dedifferentiated, invasive phenotype in response to signals from the environment. We found that p38 MAPK inhibitors SB202190 and BIRB796 induce phenotype switching from the dedifferentiated, invasive phenotype to the more differentiated phenotype in A375m2 melanoma cells cultured in three-dimensional collagen. The phenotype switch is accompanied by a morphological transition from rounded, blebby, amoeboid shape to elongated, spindle-like morphology. We performed transcriptome profiling with RNA-seq to uncover the underlying gene expression changes. Cells kept in 3D collagen were treated either with 10 µM inhibitor or with 0.1% DMSO (the vehicle) only for 48 hours and total RNA was isolated using a TRIzol-like procedure. Sequencing libraries were prepared from poly(A) RNA and sequenced with Illumina HiSeq 2500 instrument.

2020-11-28 | E-MTAB-9273 | biostudies-arrayexpress

RNA-seq of CLB-GA neuroblastoma cell line treated with Celastrol against DMSO treated controls

Project description:RNA-seq of CLB-GA neuroblastoma cell line treated with Celastrol against DMSO treated controls

| PRJEB39240 | ENA

RNA-seq of human gastric cancer cell line AGS treated with Capsaicin against DMSO

Project description:RNA-seq of human gastric cancer cell line AGS treated with Capsaicin against DMSO

| PRJEB81306 | ENA

Human WM35 melanoma cell line treated with ciclopirox and crizotinib

Project description:To generate drug signatures in human WM35 melanoma cell line. WM35 cell line was plated at 4 x 105 cells/mL overnight and treated with ciclopirox or crizotinib at 75% inhibitory concentrations (IC75, determined previously at 72h of treatment) or DMSO (vehicle) for 8h or 24h before harvest.

2018-01-01 | GSE59342 | GEO

Human A375 melanoma cell line treated with ciclopirox and crizotinib

Project description:To generate drug signatures in human A375 melanoma cell lines. A375 cell line was plated at 4 x 105 cells/mL overnight and treated with ciclopirox or crizotinib at 75% inhibitory concentrations (IC75, determined previously at 72h of treatment) or DMSO (vehicle) for 8h or 24h before harvest.

2018-01-01 | GSE59340 | GEO

Gene expression profiling in melanoma cell lines treated with THZ531 or DMSO

Project description:Gene expression profiling in melanoma cell lines treated with THZ531 or DMSO

| PRJNA766024 | ENA

Human WM35 melanoma cell line treated with trifluorothymidine(TFT) and lactimidomycin(LTM)

Project description:To generate drug signatures in human WM35 melanoma cell line. WM35 cell line was plated at 4 x 105 cells/mL overnight and treated with trifluridine or lactimidomycin at 75% inhibitory concentrations (IC75, determined previously at 72h of treatment) or DMSO (vehicle) for 8h or 24h before harvest.

2018-01-01 | GSE59341 | GEO

Human A375 melanoma cell line treated with trifluorothymidine (TFT) and lactimidomycin (LTM)

Project description:To generate drug signatures in human A375 melanoma cell lines. A375 cell line was plated at 4 x 105 cells/mL overnight and treated with trifluridine or lactimidomycin at 75% inhibitory concentrations (IC75, determined previously at 72h of treatment) or DMSO (vehicle) for 8h or 24h before harvest.

2018-01-01 | GSE59183 | GEO

RNA-seq of pancreatic CAF-derived cell line 0082T treated with Autotaxin inhibitors (IOA-289 and PF-8380) against DMSO treated controls

Project description:RNA-seq of pancreatic CAF-derived cell line 0082T treated with Autotaxin inhibitors (IOA-289 and PF-8380) against DMSO treated controls

| PRJEB80799 | ENA

Mouse melanoma cell line B16-F10 treated with G007-LK

Project description:The mouse melanoma cell line B16-F10 provided by American Type Culture Collection (ATCC® CRL-6475™) were treated with DMSO, G007-LK, WNT or G007-LK+WNT, done in triplicates for a total of 12 samples.

2021-07-01 | E-MTAB-8101 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data