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ATACseq of TNG-A derived mESCs comparing WT to Dax1, Nr5a2 and Dax1/Nr5a2 knock-out clones

ABSTRACT: ATACseq of TNG-A derived mESCs comparing WT to Dax1, Nr5a2 and Dax1/Nr5a2 knock-out clones

PROVIDER: PRJEB39929 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR4468400_1.fastq.gz	Fastqsanger.gz
	ERR4468400_2.fastq.gz	Fastqsanger.gz
	ERR4468401_1.fastq.gz	Fastqsanger.gz
	ERR4468401_2.fastq.gz	Fastqsanger.gz
	ERR4468402_1.fastq.gz	Fastqsanger.gz

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ATACseq of TNG-A derived mESCs comparing WT to Dax1, Nr5a2 and Dax1/Nr5a2 knock-out clones

Project description:ATACseq in WT, Dax1, Nr5a2 and Dax1/Nr5a2 knock-out clones of mESCs in order to determine the role of the Dax1/Nr5a2 complex on chromatin accessibility and the activity of cis-regulatory elements during differentiation.<br>This experiment is part of the study: "Mechanistic framework of lineage restriction in embryonic stem cells" by Olivieri et al.

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RNA-seq comparing WT to Dax1, Nr5a2 and Dax1/Nr5a2 knock-out clones in 2iLIF and SL differentiation conditions

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A TRIM66/DAX1/Dux axis suppresses the totipotent 2-cell-like state in murine embryonic stem cells

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