ABSTRACT: Checklist of Pipunculidae (Diptera) of continental France: Further additions to and new records of the fauna, including one species new to science
Project description:Variation in gene expression is a fundamental aspect of human phenotypic variation. Several studies have analyzed gene expression levels in populations of different continental ancestry, and concluded that there is variation across populations at a fraction of expressed genes. Here we analyze gene expression levels in African American cell lines, which differ from previously analyzed cell lines in that samples from this population have variable proportions of continental ancestry. We show that for most genes examined, gene expression varies with genetic ancestry. Keywords: Human Gene Expression Study
Project description:Analysis of genomic content of closely related Bacillus species. Refer to individual records for strain information. Refer to platform and individual sample records for experimental protocols. Keywords: other
Project description:Variation in gene expression is a fundamental aspect of human phenotypic variation. Several studies have analyzed gene expression levels in populations of different continental ancestry, and concluded that there is variation across populations at a fraction of expressed genes. Here we analyze gene expression levels in African American cell lines, which differ from previously analyzed cell lines in that samples from this population have variable proportions of continental ancestry. We show that for most genes examined, gene expression varies with genetic ancestry. Experiment Overall Design: Lymphoblastoid cell lines (LCL) for 60 HapMap CEU, 60 HapMap YRI, and 82 AFA from the Human Variation Panel were obtained from Coriell Cell Repositories. LCLs were grown in culture, total RNA was extracted and hybridized to Affymetrix HG-FOCUS arrays.
Project description:Comparative Genomic Hybridization. Analysis of genomic content of closely related Bacillus species. Refer to individual records for strain information. Refer to platform and individual sample records for experimental protocols. Keywords: other
Project description:In-depth study of the pathogenesis of NSCLC is of great significance, for the discovery of new early clinical diagnosis strategies and treatment targets for NSCLC. Epigenetics has become a research hotspot in the field of life science in recent years, and research on noncoding RNAs including PIWI-interacting RNAs (piRNAs) is an important part of this field. An increasing number of studies have shown that piRNAs play an important role in silencing transposons and regulating messenger RNA (mRNA) and long noncoding RNA (lncRNA). In the field of cancer research, piRNAs may become new molecular markers and therapeutic targets.
